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Medical Research Updates

Search BREAST CANCER, on this site, for around the world cutting - edge research and treatment findings as they are published

Wednesday, December 14, 2016

THE GILMAN JONES DAILY: Cataract surgery, The lens inside your eye- Phil H...

THE GILMAN JONES DAILY: Cataract surgery, The lens inside your eye- Phil H...:         I n cataract surgery, the lens inside your eye that has become cloudy is removed and replaced with an artificial lens (c...

THE GILMAN JONES DAILY: Cataract surgery, The lens inside your eye- Phil H...

THE GILMAN JONES DAILY: Cataract surgery, The lens inside your eye- Phil H...:         I n cataract surgery, the lens inside your eye that has become cloudy is removed and replaced with an artificial lens (c...

Friday, December 9, 2016

Drone delivers transfusion blood intact






Thursday, December 8, 2016

In findings announced yesterday, scientists from John's Hopkins University took ordinary commercial drones, swapped out their cameras for coolers and packed them with human plasma, platelets and blood cells. The drones were found to deliver their cargo in usable condition after flights lasting almost half an hour, at distances of up to 12 miles.

"For rural areas that lack access to nearby clinics, or that may lack the infrastructure for collecting blood products or transporting them on their own, drones can provide that access," says pathologist and lead author of the paper Dr. Timothy Amukele.

Although earlier studies have confirmed that drone flights do not affect the useful properties or microbe populations of human blood products, those experiments were performed on small, vial-sized samples. Here, the drones carried much larger quantities of blood, in the proportions and packaging that doctors and medical technicians would actually use on patients, with units purchased directly from the American Red Cross. Unlike Rwanda's medical delivery drones, which were custom-made for blood product delivery by Zipline, these experiments were completed with regular, commercially available S900-model machines with minimal modification.

Post-flight, the samples were tested for cell rupture, changes in pH, air bubbles and other damage that might indicate that the packages had thawed out or otherwise become unsuitable for use in transfusions. The samples were found to have arrived intact.

Although the test was performed in an unpopulated area, it is speculated that drones might be useful not only for delivery of blood products to rural medical facilities but also for distributing blood resources through urban areas. John's Hopkins pathologist and research team leader Dr. Timothy Armukele speculates that emergency medical teams may one day be able to transfuse patients on the spot by calling for a drone to bring blood of the appropriate type.

The details of the experiment have been published in the latest issue of Transfusion.



Sources:
Press Release. "Study shows blood products unaffected by drone trips" — Johns Hopkins Medicine, December 7, 2016
Kelsey D. Atherton. "Good news: It's safe to use drones to fly blood around" — Popular Science, December 7, 2016
Timothy Armukele, Paul M. Ness, Aaron A.M. Tobian, Joan Boyd, and Jeff Street. "Drone transportation of blood products" — Transfusion, November 11, 2016
Amar Toor. "Country launches world's first national drone delivery service with help from a Silicon Valley startup" — The Verge, October 13, 2016

Timothy K. Amukele, Jeff Street, Karen Carroll, Heather Miller, and Sean X. Zhang. "Drone Transport of Microbes in Blood and Sputum Laboratory Specimens" — Journal of Clinical Microbiology, August 17, 2016

Saturday, November 19, 2016

Pushing Bionic Limits at the Cyborg Olympics

Pushing Bionic Limits at the Cyborg Olympics

Disabled competitors gather to show off, and help improve, the latest in assistive technology.



Sixty-six teams of competitors from countries all around the world converged on Zurich, Switzerland, for what’s been called the first cyborg Olympics. But “Cybathlon” is much more than just a series of games—it’s a more like a super trade-show for assistive technology, where cutting edge creations that help humans grapple with disability can be displayed, and ideas exchanged about how to improve them. 

People who have been robotically enhanced are paired with researchers including roboticists and neurologists. Competitors with similar disabilities compete in Olympic-style races where the fastest time wins: One arm prosthetic race included household chores like hanging clothes and cutting bread.

The researchers use the experiences of disabled competitors to explore the limitations of current technology in an effort to develop and commercialize the unique devices being used in the games.


Saturday, October 29, 2016

Inflammation and Autoimmune Disease...The Truth of the Situation is that FOOD MATTERS

Carlsvilleproject Health

Inflammation and Autoimmune Disease

       The truth of the situation is that FOOD MATTERS. That's right, it's not just a movie (which by the way you should all watch!). Hyper-permeability of the gut, regardless of whether you can feel it or not is often a significant cause of an extremely long and ever growing list of conditions. The inflammatory cascade that takes place by any inflammatory trigger (diet, medications, infections, stress, hormonal, neurological, or metabolic) can break down the intestinal permeability and allows for the leaky gut mechanism to initiate.
Due to the variety of triggers, it is often possible to reduce an individual's immune reactivity but not cure it if leaky gut is not the primary trigger for the inflammatory process. There are multiple models of autoimmunity although it is becoming more well accepted that once you develop autoimmunity you will have increased Intestinal Permeability also.
Autoimmunity can be put into remission and this can have profound improved life consequences but it can also be turned on again if life circumstances change. It is considered "Incurable". You may be able to change the expression of it but to think that you are going to be able to take a boat load of supplements and change your diet and cure the condition you are generally going to be let down.
Waxing and waning responses are par for autoimmunity. When stress picks up despite dietary intake a person will be expected to flare up. This inflammation is initiated by increased levels of iNOS (inducible nitric oxide) which causes an immediate increase in intestinal permeability much like elevated cortisol levels from stress. Once this occurs serum protein particles leak through and become extremely reactive. Gluten is an extremely common serum protein in a situation of increased permeability simply due to the commonality of daily exposure.
If you take on too many projects, eat poorly, have limited or poor sleep patterns, then you can bet that intestinal permeability will increase and food will start to leak through.
Your immune system will then begin to recognize these proteins as other similar proteins like cerebellum, thyroid, etc... When that occurs you will experience symptoms that generally are far removed from what someone would consider to be food related since they are not felt in the gut. Instead you experience brain fog, pain, fatigue, poor sleep, anxiety, or endocrine dysfunction. When antibodies combine with our structural proteins, specific genes are turned on in a special type of immune cell in the body. Inflammatory chemicals are created called cytokines, which are strongly damaging to brain function. In fact, elevated cytokines are seen in such devastating conditions as Alzheimer's disease, Parkinson's disease, multiple sclerosis and even autism.
You see, autoimmune disease is not clinically diagnosed until you have tissue destruction. For some neurodegenerative conditions, you need up to 70 percent demyelination (nerve damage) before it will show on an MRI. You cannot afford to wait for that type of advanced destruction before taking action.

If you are symptomatic in any way and show to have antibodies or test positive on any of the tests listed above, you have Autoimmune Reactivity and that is enough to take action and make life changes to potentially stop the process from continuing. Inflammation can be a great friend in this sense. Look at it as an early warning sign and take action before it turns into a fire that rages out of control from one body tissue to another.

Monday, October 3, 2016

The Best Foods For Men's Healthy Living in The Philippines



     If you want to know the secret to keeping your doctor’s visits at a minimum, look to your kitchen. Unfortunately, as men get older, their chances of developing health problems such as high blood pressure, heart disease, high blood sugar, diabetes, and prostate cancer increase. None of those conditions are inevitable, of course, but lifestyle habits — particularly how you eat — can make a huge difference in how healthy you remain.

You can reduce the risk of these conditions by improving your diet, focusing on foods that have been shown to boost health and reduce the likelihood of a scary diagnosis.

Here are seven of the best foods men over age 50 should add to their diets, and why. If you aren’t already eating these items, there's no need to fret over what to do with them: We've got tips on how to painlessly include them.


 Mushrooms

Mushrooms ''beef up'' dishes — even vegetarian fare — by giving them a meatier taste that many men like, says Leslie Bonci, RDN, director of sports nutrition at the University of Pittsburgh Medical Center's Sports Medicine center and a sports dietitian for the university's athletics department. They only have about 20 calories per cup and contain potassium, which is helpful in offsetting the effects of sodium and in lowering blood pressure, according to the American Heart Association.

Add them to your diet: "Throw some on a salad, chop them up for chili, or grill them," Bonci says. Or try these barbecued portobello mushrooms the next time you grill.


 Tart Cherries  (We need to substitute in the Philippines)

Tart cherries can work as an anti-inflammatory agent, Bonci says. In her work consulting with sports teams, she often recommends that athletes drink tart cherry juice to reduce inflammation from vigorous training.

Cherries are very good but you can't get them in the Philippines.. For an inflammatory agent in your diet use Turmeric in your daily cooking . You can also take Turmeric by capsule. I get them at the local church where the nun prepare it.. About 4p per capsule...

  Eggs

''As men age, their muscle mass decreases," says Jim White, RDN, a spokesperson for the Academy of Nutrition and Dietetics and a personal trainer in Virginia Beach, Virginia.

"Eggs are a great source of protein," he says, and that can help with the dwindling muscle mass. Although the pendulum has swung back and forth on the healthfulness of eggs, most experts see a role for them in our diet. Eggs also have lutein, which may reduce the risk of the macular degeneration, an eye condition that can cause blindness.

Add them to your diet: Enjoy eggs for breakfast, lunch, or dinner. These nine ways to cook an egg can help you fit them into your day.
  
 Berries

Berries may reduce the risk of cancer, says Deepak Talreja, MD, a cardiologist at Eastern Virginia University Medical School in Norfolk.
Hard to impossible to get fresh berries but frozen you can buy and has all of the antioxidants present..
Also you can get berries in yorgurt here in the Philippines...

Research is ongoing, but some studies have found that blueberries, for instance, inhibit inflammation, which may decrease the risk of some cancers. A research review examining the anti-cancer properties of blueberries, published in the October 2013 issue of Anticancer Agents in Medicinal Chemistry, concluded that the little blue orbs might help inhibit the growth of cancer cells.

Blueberries aren’t the only berries that might help fight cancer. A diet that includes freeze-dried black raspberries and strawberries inhibited esophageal cancer by 30 to 70 percent and colon cancer by 80 percent, according to studies on rats done at the Medical College of Wisconsin Cancer Center in Milwaukee. Whether humans would experience the same anti-cancer benefits has yet to be proven.

Add them to your diet: Simply put, you can snack on berries straight. They're also easy to add to salads, yogurt, or hot cereals.  

  Kefir

Gut microbiota — the bacteria in our intestines — have recently garnered a lot of attention from the scientific community. It turns out that they might be key for good health, as they've been linked to how our immune system functions, how we absorb nutrients, and even how we regulate mood.

Kefir is fermented milk with prebiotics and probiotics that can help promote healthy gut microbiota. Probiotics are good bacteria, and prebiotics are the food ingredients that feed them. So kefir is a symbiotic gut health food, meaning it contains both the bacteria and the bacteria's food source. Kefir may help ward off GI problems that can occur later in life, White says. In addition, scientists have found that kefir helps reduce inflammation in the guts of mice and reduces blood sugar levels in patients with diabetes.

The difference between Kefer and Yogurt is this: 

Milk Kefir

The bacteria in milk kefir, on the other hand, can actually colonize the intestinal tract. Kefir also contains a far larger range of bacteria, in addition to containing yeasts.

Yogurt

The beneficial bacteria found in yogurt help keep the digestive tract clean and provide food for the friendly bacteria found in a healthy gut. They pass through the digestive tract and are called transient bacteria.

Add it to your diet: Kefir is sometimes referred to as the yogurt you drink. "Having a serving of kefir a day would be great," White says. You can use it like you do milk by drinking it plain, adding it to cereal, or using it in smoothies.

Avocado

Like you needed a new reason to indulge in guacamole: Avocados are loaded with heart-healthy monounsaturated fats that may help keep cholesterol levels low. And that's something that men need as they age, White says. One medium California avocado has about 230 calories, but it also has about 10 grams (g) of fiber and about 20 g of fat. Plus, avocados have also been linked to weight loss and lower levels of inflammation.

Add them to your diet: Like many of the foods on this list, avocados are easily added to dishes that you already love, like burgers, omelets, salads, sandwiches, and tacos.

 Beans

These little spheres of protein carry lots of blood benefits that may help keep heart disease and diabetes at bay. A scientific review of 26 clinical trials published in May 2014 in the Canadian Medical Association Journal found that eating 3/4 of a cup of beans daily could lower LDL (bad) cholesterol levels by 5 percent. And that, of course, can reduce your risk of heart disease and stroke.

But that isn’t the only way beans can help your blood profile. When people with type 2 diabetes consumed 1 cup of beans daily over the course of three months, they had lower blood pressure and blood sugar levels, according to a study published in October 2012 the Archives of Internal Medicine.

Add them to your diet: A cup of cooked kidney beans has approximately 225 calories, 15 g of protein, 13 g of fiber, and 1 g of fat. This makes them a great addition to salads or a filling for tacos or burritos. Also rice and beans make a perfect protein...

Eat well..Stay healthy



Monday, September 12, 2016

Forget What You've Heard About Grumpy Old Men




Forget What You've Heard About Grumpy Old Men

Carlsvilleproject Health 
Expat World-Tagum
By J. Dalessio & C. Gilman Jones

     After middle age, adults actually grow happier as they get older, despite the fact that their physical quality of life may decline. Here's the bright side of going over the hill.
Turns out the number of candles on your last birthday cake may not influence your disposition the way you might think. Instead of turning adults into grumps, growing older actually makes many of them happier.

By definition, development is a process of adaptation and successful development demands that people learn from experience, understand contingencies in their environments, approach rewarding situations, and avoid punishing ones. As a consequence, knowledge (or expertise) determines future actions, which are increasingly effective within relevant environments.

This is particularly true with expats. Most, although not all, come to the Philippines for example, with an entire life of experience behind them. Even though there is an expected adjustment period,  our wide life experience actually contributes to having a happier life. It looks like our senior years can be the best ever.

Researchers from the University of Warwick, in the United Kingdom , found that disposition improves after middle age, despite declining physical ability. Good news for some of us is that being overweight or obese doesn’t appear to make people any less happy, either.  
Acceptance, wisdom, and awareness seem to come to the fore and play a larger part in our lives, despite adversity.   Have you found yourself generally to be more tolerant than when you were young?  

A study done at the Warwick Medical School showed that heightened happiness may have something to do with better coping abilities among seniors. Makes perfect sense and would actually help us, as expats, adjust more completely to a new life….

Older people are better at dealing with life’s crises than those who are younger, a fact that was supported by a University research team. Then again, older people might just be better at letting things go.

Increased happiness could also be due to a lowering of expectations from life, with older people less likely to put pressure on themselves in the personal and professional spheres. Having the wisdom to prioritize in life; what is really important and what is actually not so important at all…
It sounds like seniors may be more “chill” than twenty-somethings.

Finally, the researchers found that those who slept between six and eight hours per day tended to score better, both physically and mentally, than those who caught less or more ZZZs.

Those of us who haven’t yet reached our happiness peaks should take a lesson from our older, wiser, and scientifically proven happier elders: Give yourself a break and get to bed early tonight.

Do you think you’ve gotten happier with age? Tell us in the comments section below!

Thursday, September 8, 2016

Heart Health.. Bundle Branch Block










Bundle Branch Block      


     Sometimes part of the heart's conduction system is "blocked." If an impulse is blocked as it travels through the bundle branches, you are said to have bundle branch block.

For the left and right ventricles to contract at the same time, an electrical impulse must travel down the right and left bundle branches at the same speed. If there is a block in one of these branches, the electrical impulse must travel to the ventricle by a different route. When this happens, the rate and rhythm of your heartbeat are not affected, but the impulse is slowed. Your ventricle will still contract, but it will take longer because of the slowed impulse. This slowed impulse causes one ventricle to contract a fraction of a second slower than the other.

The medical terms for bundle branch block are derived from which branch is affected. If the block is located in the right bundle branch, it is called right bundle branch block. If the block is located in the left bundle branch, it is called left bundle branch block.

What causes bundle branch block?

The block can be caused by coronary artery disease, cardiomyopathy, or valve disease. Right bundle branch block may also occur in a healthy heart.

What are the symptoms?

If there is nothing else wrong with your heart, you probably will not feel any symptoms of bundle branch block. In fact, some people may have bundle branch block for years and never know they have the condition. In people who do have symptoms, they may faint (syncope) or feel as if they are going to faint (presyncope).

So why should we worry about bundle branch block? Because it can be a warning sign of other, more serious heart conditions. For example, it might mean that a small part of your heart is not getting enough oxygen-rich blood. Also, researchers have found that people who have left bundle branch block may be at greater risk for heart disease than are people who do not have the condition.

How is bundle branch block diagnosed?

      
Your heart has a natural "pacemaker" called the sinoatrial (SA) node which sends an electrical impulse throughout your heart to cause it to beat (contract). That electrical impulse from the SA node first travels through the heart's upper chambers (the atria). It then passes through a small group of cells called the atrioventricular (AV) node. The AV node checks the impulse and sends it along a track called the bundle of His. The bundle of His divides into a right bundle branch and a left bundle branch, which lead to your heart's lower chambers (the ventricles).

Doctors can use an electrocardiogram (EKG or ECG) to record the electrical impulses of your heart. The electrical patterns can show bundle branch block and whether the block is located in the right or left bundle branch.
How is bundle branch block treated?

In most cases, bundle branch block does not need treatment. But patients who have bundle branch block along with another heart condition may need treatment. For example, if bundle branch block develops during a heart attack, you may need a pacemaker. After a heart attack, your heart is fragile, and bundle branch block may cause a very slow heart rhythm (bradycardia). A pacemaker helps regulate the heart's rhythm.

For patients with both bundle branch block and dilated cardiomyopathy, a new type of pacing called cardiac resynchronization treatment (CRT) may be used. Normally, pacemakers pace only one of the lower heart chambers (the ventricles) at a time. But CRT re-coordinates the beating of the two ventricles by pacing them at the same time.


Even if you do not have other conditions, you should still see your doctor regularly so that he or she can be sure there are no other changes in your heart.